Products
- Staflowin
- Ticogrip
- Ciractam
- Sulbitor
- Doxiverge
- Ivtrim
- Cregnex
- Precitaz
- Ivistin/DS/TS/Forte
- Envade
- Redactis
- Convictus /Convictus Forte/ Convictus Mega
- Ticlawin
- Zobapime 2.25
- Zidact 2.25
- Vergiflu
Generic Name: Flucloxacillin
Strengths Available : 500mg, 1g, 2g
Class : Penicillins
Usage : Staflowin is effective for the treatment of infections due to penicillinase producing staphylococci and other gram positive organisms susceptible to this anti-infective.
Approved Indications : Osteomyelitis and endocarditis. Flucloxacillin is also indicated for use as a prophylactic agent during major surgical procedures when appropriate; for example cardiothoracic and orthopaedic surgery.
MoA : Flucloxacillin is bactericidal with a similar mode of action to benzylpenicillin. It is resistant to staphylococcal penicillinase and therefore active against penicillinase-producing and non-penicillinase-producing staphylococci. It has minimum inhibitory concentrations in the range of 0.25 to 0.5g per ml.
Method of Administration : Intravenous: Dissolve 250 to 500mg in 5 to 10ml of water for injections or 1g in 15 to 20ml of water for injections. Administer by slow intravenous injection (over three to four minutes). Flucloxacillin may also be added to infusion fluids or injected (suitably diluted) into the drip tube over three to four minutes. Flucloxacillin may be added to most intravenous fluids (e.g. water for injections, sodium chloride 0.9%, glucose 5%, sodium chloride 0.18% with glucose 4%).
| Brand Names | Composition | Presentation |
|---|---|---|
| Staflowin | Flucloxacillin 500mg | 6 Capsules strip |
| Staflowin 500mg | Flucloxacillin 500mg Inj. | 1 Vial- lyophilized powder |
| Staflowin 1g | Flucloxacillin 1g Inj. | 1 Vial- lyophilized powder |
| Staflowin 2g | Flucloxacillin 2g Inj. | 1 Vial- lyophilized powder |
Generic Name: Teicoplanin
Strengths Available : 200mg , 400 mg
Class : Glycopeptides
Usage : Ticogrip is effective in threating Complicated skin and soft tissue , Bone and joint , Hospital acquired pneumonia,Community acquired pneumonia, Complicated urinary tract infections, Infective endocarditis, Peritonitis associated with continuous ambulatory peritoneal dialysis (CAPD), Bacteraemia that occurs in association with any of the indications listed above
Approved Indications : Complicated skin and soft tissue infections, Bone and joint infections, Hospital acquired pneumonia, Community acquired pneumonia, Complicated urinary tract infections, Infective endocarditis, Peritonitis associated with continuous ambulatory peritoneal dialysis (CAPD), Bacteraemia that occurs in association with any of the indications listed above
MoA : Teicoplanin inhibits the growth of susceptible organisms by interfering with cell-wall biosynthesis at a site different from that affected by beta-lactams. Peptidoglycan synthesis is blocked by specific binding to D-alanyl-D-alanine residues.
Method of Administration : Teicoplanin should be administered by the intravenous or intramuscular route. The intravenous injection may be administered either as a bolus over 3 to 5 minutes or as a 30-minute infusion.
Only the infusion method should be used in neonates.
| Brand Names | Composition | Presentation |
|---|---|---|
| Ticogrip 200 | Teicoplanin 200mg Inj. | 1 Vial- lyophilized powder |
| Ticogrip 400 | Teicoplanin 400mg Inj. | 1 Vial- lyophilized powder |
Generic Name: Cefpirome & Sulbactam
Strengths Available : 1.5 g & 3g
Class : Cephalosporins & beta lactamase inhibitors
Usage : Ciractam is effective in treating Lower respiratory tract infections, Complicated Lower and Upper UTI,Bacteremia/Septicaemia, Infections in neutropenic and Immuno-compromised patients, Skin & soft tissues infections, and severe infections in ICU
Approved Indications : Lower respiratory tract infections, Complicated Lower and Upper UTI,Bacteremia/Septicaemia, Infections in neutropenic and Immuno-compromised patients, Skin & soft tissues infections, Severe infections in ICU
MoA : Cefpirome binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.
Sulbactam is a Beta lactamase inhibitor and acts primarily by irreversible inactivation of Beta lactamases.
Method of Administration : 1.5 g -3 gm every 12 hour via IV injection over 3-5 minutes or infuse over 20-30 minutes
| Brand Names | Composition | Presentation |
|---|---|---|
| Ciractam 1.5g | Cefpirome 1g & Sulbactam 500mg Inj. | 1 Vial- lyophilized powder |
| Ciractam 3g | Cefpirome 2g & Sulbactam 1g Inj. | 1 Vial- lyophilized powder |
Generic Name: Ampicillin & Sulbactam
Strengths Available : 1.5 g & 3g
Class : Penicillin & beta lactamase inhibitors
Usage : Sulbitor is effective in treating community acquired pneumonia , HAP/VAP, Skin and skin structure infections , Intra-abdominal infections, and also used as Surgical prophylaxis
Approved Indications : Community acquired pneumonia , HAP/VAP, Skin and skin structure infections , Intra-abdominal infections, Surgical prophylaxis
MoA : Ampicillin is similar to benzyl penicillin in its bactericidal action against susceptible organisms during the stage of active multiplication. It acts through the inhibition of cell wall mucopeptide biosynthesis. Ampicillin has a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria.
Sulbactam is a lactamase inhibitor and acts primarily by irreversible inactivation of lactamases.
Method of Administration : For IV administration, the dose can be given by slow intravenous injection over at least 10–15 minutes or can also be delivered, in greater dilutions with 50–100 mL of a compatible diluent as an intravenous infusion over 15–30 minutes.
| Brand Names | Composition | Presentation |
|---|---|---|
| Sulbitor 1.5g | Ampicillin1g & Sulbactam 500mg Inj. | 1 Vial- lyophilized powder |
| Sulbitor 3g | Ampicillin 2g & Sulbactam 1g Inj. | 1 Vial- lyophilized powder |
Generic Name: Doxycycline
Strengths Available : 100mg & 200 mg
Class : Tetracyclines
Usage : Doxiverge is effective in treating Atypical pneumonia, Urinary tract infections, Malaria, Mediterranean spotted fever, Typhus fever, Acute brucellosis, and Cervical chlamydia infections
Approved Indications : Atypical pneumonia, Urinary tract infections, Malaria, Mediterranean spotted fever, Typhus fever, Acute brucellosis, Cervical chlamydia infections
MoA : Doxycycline has bacteriostatic effect blocks protein synthesis at the bacterial ribosome level. The antibiotic connects permanently to 30S (the small ribosome subunit). Resulting in a blocking of the binding of aminoacyl-tRNA (acceptor site) on the mRNA-ribosome complex. This connection terminates the growth of bacterial cells.
Method of Administration : The contents of the vial should be reconstituted with 10 mL of Sterile Water for Injection/nacl/vitamin c
Each 100 mg of doxycycline (i.e., withdraw entire solution from the 100 mg vial) is further diluted with 100 to 1000 mL of the intravenous solutions listed below
0.9% Sodium Chloride Injection
5% Dextrose Injection
Ringer's Injection
| Brand Names | Composition | Presentation |
|---|---|---|
| Doxiverge 100mg | Doxycycline 100mg Inj. | 1 Vial- lyophilized powder |
| Doxiverge PLUS100mg | Doxycycline 100mg Inj. | 1 Vial- lyophilized powder + Ready to administer kit |
| Doxiverge 200g | Doxycycline 200mg Inj. | 1 Vial- lyophilized powder |
Generic Name: Trimethoprim & Sulphamethoxazole
Strengths Available : 5ml Ampoule
Class : Sulfonamides
Usage : IVTRIM is effective in treating Pneumocystis (Carinii) Jiroveci Pneumonia, Shigella Enteritis, Severe UTIs, toxoplasmosis & Nocardiosis
Approved Indications : Pneumocystis (Carinii) Jiroveci Pneumonia, Shigella Enteritis, Severe UTIs, toxoplasmosis, Nocardiosis
MoA : Co-trimoxazole is generally bactericidal; it acts by sequential blockade of folic acid enzymes in the synthesis pathway. The sulfamethoxazole component inhibits formation of dihydrofolic acid from para-aminobenzoic (PABA), whereas trimethoprim inhibits dihydrofolate reductase.
Method of Administration : It is recommended that Co-Trimoxazole 16 mg/80 mg per ml for Infusion is diluted according to the following schedules:
One ampoule (5 ml) added to 125 ml infusion solution.
Two ampoules (10 ml) added to 250 ml infusion solution.
Three ampoules (15 ml) added to 500 ml infusion solution.
| Brand Names | Composition | Presentation |
|---|---|---|
| Ivtrim | Trimethoprim 80mg & Sulphamethoxazole 400mg Inj. | 1 Vial- lyophilized powder |
Cregnex
Generic Name: Polymyxin B
Strengths Available : 500000 IU, 750000 IU
Class : Polymyxins
Usage : CREGNEX is effective in treating serious infections caused by Gram negative bacteria including LRTI, UTI when commonly used systemic antibacterial agents may be contraindicated or may be ineffective because of bacterial resistance, Post surgical infections in hospitalized patients, Neonatal sepsis, Nosocomial infections & Ventilator associated pneumonia (VAP)
Approved Indications : Serious infections caused by Gram negative bacteria including LRTI, UTI when commonly used systemic antibacterial agents may be contraindicated or may be ineffective because of bacterial resistance, Post surgical infections in hospitalized patients, Neonatal sepsis, Nosocomial infections,Ventilator associated pneumonia (VAP)
MoA : Polymyxin B is a surface active agent which penetrates into and disrupts the bacterial cell membrane. Polymyxin B is polycationic that works by damaging the cell membrane.This effect is bactericidal. Polymyxins are selective for gram negative bacteria that have hydrophobic outer membrane.
Method of Administration : For IV use, dilute the contents in 300-500 ml NS or D5W and infuse over 60-90 minnutes
For IM use ,reconstitute vial with 2 mL SWI , NS, or procaine HCl 1% solution and give deep into upper outer quadrant of gluteal muscles.
Intrathecal (IT): reconstitute vial with10 mL NS; DO NOT use procaine HCl for IT
| Brand Names | Composition | Presentation |
|---|---|---|
| Cregnex 500000IU | Polymyxin B 500000IU Inj. | 1 Vial- lyophilized powder |
| Cregnex 1000000IU | Polymyxin B 1000000IU Inj. | 1 Vial- lyophilized powder |
Generic Name: Piperacillin & Tazobactam
Strengths Available : 2.25 g, 4.5 g
Class : Penicillins and ß lactamase inhibitors
Usage : Prectaz is effective in treating Appendicitis, Peritonitis, Skin and soft tissue infections, Lower respiratory tract infections, infection in neutropenic patients, burn & Intra-abdominal infections
Approved Indications : Appendicitis, Peritonitis, Skin and soft tissue infections, Lower respiratory tract infections, infection in neutropenic patients, burns, Intra-abdominal infections
MoA : Piperacillin inhibits bacterial cell wall synthesis by binding to one or more of the penicillin binding proteins (PBPs); which in turn inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls, thus inhibiting cell wall biosynthesis. Tazobactam inhibits the action of bacterial beta-lactamases. It is added to the extended spectrum beta-lactam antibiotic piperacillin. It broadens the spectrum of piperacillin by making it effective against organisms that express beta-lactamase and would normally degrade piperacillin.
Method of Administration : Intravenous Administration. Reconstituted vial is stable for 24 hours if stored at room temperature or after 48 hours if stored at 2-8 degrees C
| Brand Names | Composition | Presentation |
|---|---|---|
| Precitaz 2.25g | Piperacillin 2g & Tazobactam 0.25g Inj. | 1 Vial- lyophilized powder |
| Precitaz 4.5g | Piperacillin 4g & Tazobactam 0.5g Inj. | 1 Vial- lyophilized powder |
Generic Name: Colistimethate sodium
Class : Polymyxins
Usage : INVISTIN is effective in treating Serious infections caused by Gram negative bacteria including LRTI, UTI when commonly used systemic antibacterial agents may be contraindicated or may be ineffective because of bacterial resistance, Post surgical infections in hospitalized patients, Neonatal sepsis, Nosocomial infections, & Ventilator –associated pneumonia (VAP)
Approved Indications : serious infections caused by Gram negative bacteria including LRTI, UTI when commonly used systemic antibacterial agents may be contraindicated or may be ineffective because of bacterial resistance, Post surgical infections in hospitalized patients, Neonatal sepsis, Nosocomial infections, Ventilator –associated pneumonia (VAP)
MoA : Colistimethate sodium is a surface active agent which penetrates into and disrupts the bacterial cell membrane. Colistimethate is polycationic that works by damaging the cell membrane.This effect is bactericidal. Polymyxins are selective for gram negative bacteria that have hydrophobic outer membrane.
Method of Administration : Can be given as 50 ml IV infusion over 30 minutes
| Brand Names | Composition | Presentation |
|---|---|---|
| Ivistin | Colistimethate sodium 1M IU Inj. | 1 Vial- lyophilized powder |
| Ivistin DS | Colistimethate sodium 2M IU Inj. | 1 Vial- lyophilized powder |
| Ivistin TS | Colistimethate sodium 3M IU Inj. | 1 Vial- lyophilized powder |
| Ivistin Forte | Colistimethate sodium 4M IU Inj. | 1 Vial- lyophilized powder |
Generic Name: Imipenem & Cilastatin
Class : Carbapenems
Usage : Envade is effective in treating lower respiratory tract infections, Urinary tract infections , Intra-abdominal infections, Gynecological infections, Life-threatening infections (Septicemia, Endocarditis, Shock), Bone and joint infections, Polymicrobial infections
Approved Indications : Lower respiratory tract infections, Urinary tract infections , Intra-abdominal infections, Gynecological infections, Life-threatening infections (Septicemia, Endocarditis, Shock), Bone and joint infections, Polymicrobial infections
MoA : Envade consists of two components: (1) Imipenem, a derivative of thienamycin, a carbapenem antibiotic; and (2) Cilastatin sodium, a specific inhibitor of dehydropeptidase-I, a renal enzyme which metabolizes and inactivates imipenem. Cilastatin blocks the metabolism of Imipenem in the kidney, so that concomitant administration of Imipenem and Cilastatin allows antibacterial levels of Imipenem to be attained in the urine.
Method of Administration : Each 500 mg dose should be given by intravenous administration over 20 to 30 minutes.
| Brand Names | Composition | Presentation |
|---|---|---|
| Envade | Imipenem 500mg & Cilastatin 500mg Inj. | 1 Vial- lyophilized powder |
Generic Name: Tigecycline
Class : Glycylcycline
Usage : REDACTIS is effective in treating Complicated intra-abdominal Infections, Complicated skin & skin structure infections & Community-acquired Pneumonia.
Approved Indications : Complicated intra-abdominal Infections, Complicated skin & skin structure infections , Community-acquired Pneumonia.
MoA : Tigecycline is bacteriostatic and is a protein synthesis inhibitor by binding to the 30S ribosomal sub unit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation.
Method of Administration : Intravenous infusion should be administered over approximately 30 to 60 minutes every 12 hours.
| Brand Names | Composition | Presentation |
|---|---|---|
| Redactis | Togecycline 50mg Inj. | 1 Vial- lyophilized powder |
Generic Name: Cefoperazone & Sulbactam
Class : Cephalosporins and Beta Lactamase Inhibitors
Usage : Effective in treating Respiratory tract infections (Upper and Lower), Urinary tract infections (Upper and Lower) ,Peritonitis, Cholecystitis, Cholangitis, and Other Intra-abdominal infections. Septicemia, Meningitis , Skin and soft tissue Infections, Bone and joint Infections, Pelvic inflammatory disease, Endometritis, Gonorrhea, and other Infections of the genital tract.
Approved Indications : Respiratory tract infections (Upper and Lower) , Urinary tract infections (Upper and Lower) ,Peritonitis, Cholecystitis, Cholangitis, and Other Intra-abdominal infections. Septicemia, Meningitis , Skin and soft tissue Infections
Bone and joint Infections, Pelvic inflammatory disease, Endometritis, Gonorrhea, and other Infections of the genital tract.
MoA : Cefoperazone, a bactericidal antibiotic, inhibits bacterial cell wall synthesis of actively dividing cells by binding to one or more penicillin binding proteins (PBPs). Sulbactam is a Beta-lactamase inhibitor and acts primarily by irreversible inactivation of Beta -lactamases.
Method of Administration : Each vial of sulbactam/cefoperazone should be reconstituted with the appropriate amount of 5% Dextrose in Water, 0.9% Sodium Chloride Injection or Sterile Water for Injection and then diluted to 20 ml with the same solution followed by administration over 15 to 60 minutes.
| Brand Names | Composition | Presentation |
|---|---|---|
| Convictus | Cefoperazone 500mg & Sulbactam 500mg Inj. | 1 Vial- lyophilized powder |
| Convictus Forte | Cefoperazone 1g & Sulbactam 500mg Inj. | 1 Vial- lyophilized powder |
| Convictus Mega | Cefoperazone 2g & Sulbactam 1g Inj. | 1 Vial- lyophilized powder |
Generic Name: Ticarcillin & Clavulanic acid
Strengths Available : 3.1g
Class : Carboxypenicillin & Beta Lactamase Inhibitor
Usage : Ticlawin is effective in treating Septicemia, Lower respiratory infections, Bone and joint infections, Skin and skin structure infections, Urinary tract infections,and Intra-abdominal infections
Approved Indications : Septicemia, Lower respiratory infections, Bone and joint infections, Skin and skin structure infections, Urinary tract infections, Intra-abdominal infections
MoA : Ticarcillin disrupts bacterial cell wall development by inhibiting peptidoglycan synthesis and/or by interacting with penicillin-binding proteins.
Clavulanic acid is produced by the fermentation of Streptomyces clavuligerus. It is a Beta-lactam structurally related to the penicillins and possesses the ability to inactivate a wide variety of Beta-lactamases by blocking the active sites of these enzymes. Clavulanic acid is particularly active against the clinically important plasmid-mediated Beta-lactamases frequently responsible for transferred drug resistance to penicillins and cephalosporins.
Method of Administration : The 3.1-gram vial should be reconstituted by adding approximately 13 mL of Sterile Water for Injection or Sodium Chloride Injection.Â
Intravenous Infusion: The dissolved drug should be further diluted to desired volume using the recommended solution to a concentration between 10 mg/mL to 100 mg/mL. The solution of reconstituted drug may then be administered over a period of 30 minutes.
| Brand Names | Composition | Presentation |
|---|---|---|
| Ticlawin | Ticarcillin 3g & Clavulanic acid 100mg Inj. | 1 Vial- lyophilized powder |
Generic Name: Cefepime & Tazobactam
Strengths Available : 2.25g
Class : Cephalosporins
Usage : Zobapime is effective in treating UTI, Febrile neutropenia(FN), Moderate to severe pneumonia, cIAIs, and Uncomplicated SSSI
Approved Indications : UTI, Febrile neutropenia(FN), Moderate to severe pneumonia, cIAIs, Uncomplicated SSSI
MoA : Cefepime -Inhibits bacterial cell wall synthesis by binding to one or more of the penicillin-binding proteins (PBPs) which in turn inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls, thus inhibiting cell wall biosynthesis.
Tazobactam -Tazobactam despite sharing the - lactam - ring that is characteristic of beta-lactam antibiotics. This similarity in chemical structure helps the Tazobactam to act as a inhibitor of beta-lactamase enzyme secreted by certain bacteria that are resistant to beta-lactam antibiotics.
Method of Administration : Cefepime+ Tazobactam can be injected as slow IV over 5 Minutes or as an infusion over 30 Minutes.
| Brand Names | Composition | Presentation |
|---|---|---|
| Zobapime 2.25 | Cefepime 2g & Tazobactam 250mg Inj. | 1 Vial- lyophilized powder |
Generic Name: Ceftazadime & Tazobactam
Strengths Available : 2.25g
Class : Cephalosporins
Usage : Zidact is effective in treating Lower Respiratory Tract Infections- including pneumonia, Skin and Skin-Structure Infections, Urinary Tract Infections, both complicated and uncomplicated, Bacterial Septicemia, Bone and Joint Infections, Gynecologic Infections, Intra-abdominal Infections & Central Nervous System Infections
Approved Indications : Lower Respiratory Tract Infections- including pneumonia, Skin and Skin-Structure Infections, Urinary Tract Infections, both complicated and uncomplicated, Bacterial Septicemia, Bone and Joint Infections, Gynecologic Infections, Intra-abdominal Infections, Central Nervous System Infections
MoA : Ceftazidime- Semisynthetic, broad-spectrum antibacterial derived from cephaloridine and used especially for Pseudomonas and other gram-negative infections in debilitated patients.The bactericidal activity of ceftazidime results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins
Tazobactam -Tazobactam despite sharing the - lactam - ring that is characteristic of beta-lactam antibiotics. This similarity in chemical structure helps the Tazobactam to act as a inhibitor of beta-lactamase enzyme secreted by certain bacteria that are resistant to beta-lactam antibiotics.
Method of Administration : Reconstitute vial with sterile WFI , and further dilute with50ml or 100 ml 0.9 %NaCl, Dextrose 5% , M/6 Sodium Lactate injection & infuse over 30 minutes
| Brand Names | Composition | Presentation |
|---|---|---|
| Zidact 2.25 | Ceftazidime 2g & Tazobactam 250mg Inj. | 1 Vial- lyophilized powder |
Generic Name: Favipiravir
Strengths Available : 200mg,400mg
Class : Nucleoside, Antiviral
Usage : Mild to Moderate COVID19 Patients,Treatement of Influenza A & B Virus, Ebola virus
Approved Indications : Mild ro Moderate COVID-19 Patients
MoA : The active form, favipiravir-RTP binds to and inhibits the RNA-dependent RNA polymerase (RdRp), preventing viral transcription and replication.Incorporation of favipiravir-RTP into a newly formed RNA strand preventing its elongation and proliferation of the viral genome.
Competitive binding of RNA-dependent RNA polymerase by the favipiravir-RTP and purine nucleosides, which ultimately affects viral replication and transcription.
Method of Administration : Oral Administration, On day 1, 1800mg BID i.e. Morning & Evening 9 tablets respectively. Day2 to Day14 800mg BID i.e.4 tablets Morning & Evening respectively.
- Oxihalt
- Glutaverge
- Glutaverge Sachet
- Prabinex
- Prabinex HD
- Vosimol/Vosimol Plus
- Panverge D
- Tolerab D
- Tancyvit
- Divify
- Prabinex 500 mg
- Prabinex Z
Generic Name: Injection Glutathione
Strengths Available : 600 mg
Class : Tripetides with 3 amino acids glutamic acid, cysteine, and glycine
Approved Indications : Critically ill patients, Liver disorders,Cancer patients,Chronic illness, GI compromised patients,Neurodegenerative disorders
MoA : GSH is an extremely important cell protectant. It directly quenches reactive hydroxyl free radicals, other oxygen-centered free radicals, and radical centers on DNA and other biomolecules. GSH is a primary protectant of skin, lens, cornea, and retina against radiation damage and other biochemical foundations of P450 detoxification in the liver, kidneys, lungs, intestinal, epithelia and other organs
GSH is the essential cofactor for many enzymes that require thiol-reducing equivalents, and helps keep redox-sensitive active sites on enzyme in the necessary reduced state. Higher-order thiol cell systems, the metallothioneins, thioredoxins and other redox regulator proteins are ultimately regulated by GSH levels—and the GSH/GSSG redox ratio. GSH/GSSG balance is crucial to homeostasis—stabilizing the cellular biomolecular spectrum, and facilitating cellular performance and survival.
Method of Administration : IV Drip :Dissolve with 5ml sterile water for injection ; the solution is further diluted into 250 ml or 500ml with Normal saline or 5 % dextrose for IV infusion
IM Injection : :Dissolve with 5ml sterile water for injection . Inject the solution intramascularly, preferably in gluteal region.
| Brand Names | Composition | Presentation |
|---|---|---|
| Oxihalt | Glutathione Injection 600 mg IV/IM | Injectable |
Molecule: Available as L-alanyl-L-glutamine dipeptide in 20%
Class : Amino acids
Approved Indications : Is indicated as part of an intravenous parenteral nutrition regimen as a supplement to amino acid solutions or an amino acid containing infusion regimen, e.g. in patients in hypercatabolic and/or hypermetabolic states
MoA : Works by helping in gut functioning, the immune system and other essential processes in the body; contributing towards protein construction; strengthening the immune system; helping in metabolism of sugars; reducing the level of cholesterolÂ
Method of Administration : 1.5-2.0 ml /kg /day Can be administered along with TPN or alone Should be mixed with NS in 1 : 1 ratio Infusion rate : 0.5 ml /minute
| Brand Names | Composition | Presentation |
|---|---|---|
| Glutaverge | 50ml | Injectable |
Molecule: L Glutamine, Sodium selenite & Zinc sulphate
Class : Nutritional Supplement
Approved Indications : Patients with GI surgery, Critical Illness, Pre and Post operative conditions, Compromised immunity, Burns
Method of Administration : Dissolve the content in 100 ml of water
| Brand Names | Composition | Presentation |
|---|---|---|
| Glutaverge Sachet | Available as Sachet | Injectable |
Molecule: Thiamine Hydrochloride, Riboflavin, Pyridoxine Hydrochloride, Ascorbic Acid, Nicotinamide, Glucose (as Monohydrate) 1000 mg
Class : Water soluble vitamins
Approved Indications : particularly in alcoholism, where a severe depletion of thiamine can lead to Wernicke's encephalopathy, after acute infections, post-operatively, Post Hemodialysis, Sepsis and septic shock
MoA : The B group of vitamins are involved in the development and maintenance of the nervous system (brain and nerves) and the formation of blood cells. Vitamin C is an antioxidant and is responsible for maintaining healthy cell structure and producing an important protein, known as collagen, which is found in the skin, bone, cartilage and tendons.
Method of Administration : Prabinex Intravenous High Potency, Concentrate for Solution for Infusion should be administered by drip infusion. Equal volumes of the contents of ampoules number 1 and 2 should be added to 50 ml to 100 ml physiological saline or 5% glucose and infused over 30 minutes
| Brand Names | Composition | Presentation |
|---|---|---|
| Prabinex | Two ampoules of 5 ml | Injectable |
Molecule: Ascorbic acid
Class : Water soluble vitamins
Approved Indications : Sepsis related organ failure, Adjuvant therapy in viral infections, Synergism with antibiotics for infections caused by Streptococcal, Staphylococcal , E.coli, and Pseudomonas strains. Supportive therapy in ARDS, and Acute Lung Injury, Supportive therapy in patients with Cancer by inhibiting tumor growth and synergizing with Chemotherapy agents
MoA : Ascorbic acid is an essential water soluble vitamin that acts as a cofactor and antioxidant. Ascorbic acid is an electron donor used for collagen hydroxylation, carnitine biosynthesis, and hormone/amino acid biosynthesis. It is required for connective tissue synthesis as well as iron absorption and storage
Method of Administration : 1.5 g of Prabinex HD is diluted with 50 ml of 0.9 % saline
| Brand Names | Composition | Presentation |
|---|---|---|
| Prabinex HD | 1.5 g | Injectable |
Molecule: Inj. Paracetamol IV
Class : Analgesic and antipyretic
Approved Indications : Indicated for the short-term treatment of moderate pain, especially following surgery
For the short-term treatment of fever, when administration by intravenous route is clinically justified
In urgent need to treat pain or hyperthermia and / or when other routes of administration are not possible
MoA : The exact mechanism of action of paracetamol is still unclear
It is thought to exert its analgesic activity by inhibiting the synthesis of prostaglandins in the CNS (central acting) and peripherally blocking pain impulse generation
It is thought to exert its analgesic activity by inhibiting the synthesis of prostaglandins in the CNS (central acting) and peripherally blocking pain impulse generation
Method of Administration : The paracetamol solution is administered as a 15-minute intravenous infusion.
| Brand Names | Composition | Presentation |
|---|---|---|
| Vosimol/Vosimol Plus | 1000 mg / 100 ml | Injectable |
Composition: Pantoprazole 40 + Domperidone 30 mg
Dosage : Once Daily or Twice Dialy as advised by physician
Usage : Its a proton pump inhibitor used in the treatment of stomach ulcers, gastroesophageal reflux disease (GERD) and other acidity-related disorders. It decreases the acid produced in the stomach and helps in promoting healing of ulcers
Approved Indications : In GERD and other acidity related disorders
| Brand Names | Composition | Presentation |
|---|---|---|
| Panverge D | Pantoprazole 40 + Domperidone 30 mg | 10s pack(tablets) |
Composition: Rabeprazole 20 mg + Domperidone 30 mg
Dosage : Once Daily
Usage : This tablet is used in the treatment of stomach ulcers, Gastroesophageal reflux disease (GERD) and other acidity related disorders by decreasing the acid produced in the stomach.
Approved Indications : In GERD and other acidity related disorders
| Brand Names | Composition | Presentation |
|---|---|---|
| Tolerab D | Rabeprazole 20 mg + Domperidone 30 mg | 10s pack(tablets) |
Composition: Multi vitamin , Minerals & Antioxidant soft gel capsules
Dosage : Once or Twice Daily as recommended
Usage : Capsule is a combination of essential minerals and vitamins that helps in blood formation, bone strengthening, and other vital functions. It is used to treat vitamin deficiencies, anemia, and nerve-related symptoms. This capsule helps to increase physical strength, immunity power. It improves nerve function and blood circulation. It enhances the energy levels and supports in weight management.
Approved Indications : To restore nutritional deficiency states
| Brand Names | Composition | Presentation |
|---|---|---|
| Tancyvit | Multi vitamin , Minerals & Antioxidant soft gel capsules | 10s pack(Capsules) |
Composition: VITAMIN D3 60000 IU ORALLY DISINTEGRATING STRIPS
Dosage : One Strip/Week
Usage : In vitamin D deficiency states and prevent complications of Hypovitaminosis, Post menopausal osteoporosis, As an adjunct in Diabetes
Approved Indications : Hypovitaminosis, Post menopausal osteoporosis, As an adjunct in Diabetes
| Brand Names | Composition | Presentation |
|---|---|---|
| Divify | VITAMIN D3 60000 IU ORALLY DISINTEGRATING | 8 Strips |
Composition: ascorbic acid 500 mg
Approved Indications : Benefits are as follows:
* Contribute to normal functioning of immune system
* Boosts immune system to effectively protect from Covid 19
* Powerful antioxidant, relieves symptoms of asthma
* Protects against cough and common cold
* Prevents cancer and heart disease - aids lowering hypertensio
| Brand Names | Composition | Presentation |
|---|---|---|
| Prabinex 500 mg | Ascorbic acid 500 mg | 15s packing(tablets) |
Composition: Ascorbic acid 500 mg + zinc 20 mg
Approved Indications : Benefits are as follows:
* Reduced inflamaton
* Protectsfrom free radicals and oxidaive stress
* Enhances immunity system
| Brand Names | Composition | Presentation |
|---|---|---|
| Prabinex Z | Ascorbic acid 500 mg + zinc 20 mg | 15s packing(tablets) |
- Tenlicreat
- Tenlicret M Plus
- Zyvana
- Tenlicret
- Tenlicret M
- Zyvana M1/M2
- Zyvana M2 Forte
- Confirmin 500/1000 mg
- Numbnil
- Entivon
- Entivon Plus
Composition: TENELIGLIPTIN 20 mg tablet
Dosage : Once Daily
Usage : Teneligliptin is a Novel Dipeptidyl Peptidase IV inhibitors for the treatment of type 2 diabetes with minimal risk of hypoglycemia and weight gain. TENeLIgliptin act on inCRETins with elevation of activated glucagon-like peptide 1 (GLP-1) levels and the resulting suppression of postprandial hyperglycemia.
Approved Indications : In treatment of Type 2 diabetes mellitus
| Brand Names | Composition | Presentation |
|---|---|---|
| Tenlicret | Teneligliptin 20 mg | 10s pack(tablets) |
Composition: TENELIGLIPTIN 20 + METFORMIN 1000 mg tablet
Dosage : Once Daily
Usage : Teneligliptin is a Novel Dipeptidyl Peptidase IV inhibitors for the treatment of type 2 diabetes with minimal risk of hypoglycemia and weight gain. TENeLIgliptin act on inCRETins with elevation of activated glucagon-like peptide 1 (GLP-1) levels and the resulting suppression of postprandial hyperglycemia.
Approved Indications : In treatment of Type 2 diabetes mellitus
| Brand Names | Composition | Presentation |
|---|---|---|
| Tenlicret M Plus | TENELIGLIPTIN 20 + METFORMIN 1000 mg tablet | 10s pack(tablets) |
Composition: Glimepiride 1mg/2mg tablets
Dosage : Once Daily
Usage : Glimipiride 1/2 mg tablet is a long-acting oral anti-diabetic which lower the blood sugar level. It is used only in patients diagnosed with Type II Diabetes. It may be used along with Insulin or other medicines in order to achieve better control over the blood sugar levels. This medicine, when taken along with a controlled diet and regular exercise routine, may give better results.
Approved Indications : For Type 2 diabetes mellitus patients for glycemic control
| Brand Names | Composition | Presentation |
|---|---|---|
| Zyvana | Glimepiride 1mg/2mg | 10s pack(tablets) |
Composition: TENELIGLIPTIN 20 mg tablet
Dosage : Once Daily
Usage : Teneligliptin is a Novel Dipeptidyl Peptidase IV inhibitors for the treatment of type 2 diabetes with minimal risk of hypoglycemia and weight gain. TENeLIgliptin act on inCRETins with elevation of activated glucagon-like peptide 1 (GLP-1) levels and the resulting suppression of postprandial hyperglycemia.
Approved Indications : In treatment of Type 2 diabetes mellitus
| Brand Names | Composition | Presentation |
|---|---|---|
| Tenlicret | Teneligliptin 20 mg | 10s pack(tablets) |
Composition: TENELIGLIPTIN 20 + METFORMIN 500 mg tablet
Dosage : Once Daily
Usage : Teneligliptin is a Novel Dipeptidyl Peptidase IV inhibitors for the treatment of type 2 diabetes with minimal risk of hypoglycemia and weight gain. TENeLIgliptin act on inCRETins with elevation of activated glucagon-like peptide 1 (GLP-1) levels and the resulting suppression of postprandial hyperglycemia.
Approved Indications : In treatment of Type 2 diabetes mellitus
| Brand Names | Composition | Presentation |
|---|---|---|
| Tenlicret M | TENELIGLIPTIN 20 + METFORMIN 500 mg | 10s pack(tablets) |
Composition: Glimepiride 1mg/2mg + Metformin 500 mg tablets
Dosage : Once Daily
Usage : It is an effective choice medicine used to control high blood glucose levels in patients with type II diabetes. Patients are advised to maintain a strict exercise and diet regimen along with this medicine to get the best possible effect.
Approved Indications : For Type 2 diabetes mellitus patients inadequately controlled on monotherapy.
| Brand Names | Composition | Presentation |
|---|---|---|
| Zyvana M1/M2 | Glimepiride 1mg/2mg + Metformin 500 mg | 10s pack(tablets) |
Composition: Glimepiride 1mg/2mg + Metformin 500 mg tablets
Dosage : Once Daily
Usage : It is an effective choice medicine used to control high blood glucose levels in patients with type II diabetes. Patients are advised to maintain a strict exercise and diet regimen along with this medicine to get the best possible effect.
Approved Indications : For Type 2 diabetes mellitus patients inadequately controlled on monotherapy.
| Brand Names | Composition | Presentation |
|---|---|---|
| Zyvana M1/M2 | Glimepiride 1mg/2mg + Metformin 500 mg | 10s pack(tablets) |
Composition: Glimepiride 2mg + Metformin 1000 mg tablets
Dosage : Once Daily
Usage : It is an effective choice medicine used to control high blood glucose levels in patients with type II diabetes. Patients are advised to maintain a strict exercise and diet regimen along with this medicine to get the best possible effect.
Approved Indications : For Type 2 diabetes mellitus patients uncontrolled on low dose dual therapy.
| Brand Names | Composition | Presentation |
|---|---|---|
| Zyvana M2 Forte | Glimepiride 2mg + Metformin 1000 mg | 10s pack(tablets) |
Composition: Metformin Hydrochloride 500 & 1000 mg
Dosage : Once Daily or Twice Dialy as advised by physician
Usage : Metformin 500 mg/ 1000 mg Tablet is an effective first choice medicine used to control high blood glucose levels in patients with type II diabetes. Patients are advised to maintain a strict exercise and diet regimen along with this medicine to get the best possible effect. It helps in minimizing the risk of diabetes-associated complications such as blindness, kidney damage, stroke and heart attack.
Approved Indications : As a first line therapy in newely diagnosed diabetic patients
| Brand Names | Composition | Presentation |
|---|---|---|
| Confirmin 500/1000 mg | Metformin Hydrochloride 500 & 1000 mg | 15s packing(tablets) |
Composition: Ashwagandha, Piper Longum, Zingiber Officinale,Mustard Oil & Aleovera-a total foot care cream
Dosage : Apply 3 times a day in palms,soles & other affected areas
Usage : Total foot care cream effective in Burning feet syndrome, Numbness, Tingling pain, shooting pain in Soles or palms.
Approved Indications : Burning feet syndrome, Numbness, Tingling pain, shooting pain in Soles or palms
| Brand Names | Composition | Presentation |
|---|---|---|
| Numbnil | Ashwagandha, Piper Longum, Zingiber Officinale,Mustard Oil & Aleovera | 1 tube(cream) |
Composition: Methylcobalamin 750 mcg + Pregabalin 75 mg capsules
Dosage : Once/Twice daily as recommended
Usage : Level “A” recommended for relief of painful diabetic peripheral neuropathy with excellent tolerability.
Approved Indications : In management of mild to moderate stages of Diabetic Peripheral Neuropathy
| Brand Names | Composition | Presentation |
|---|---|---|
| Entivon | Methylcobalamin 750 mcg + Pregabalin 75 mg | 10s pack(capsules) |
Composition: Nortriptyline 10 mg +Methylcobalamin 1500 mcg + Pregabalin 75 mg SR tablets
Dosage : Once Daily
Usage : This medication is used to treat pain caused by nerve damage due to diabetes or spinal cord injury. This medication is also used to treat pain in people with fibromyalgia.
Approved Indications : In management of advanced stages of diabetic peripheral neuropathy
| Brand Names | Composition | Presentation |
|---|---|---|
| Entivon Plus | Nortriptyline 10 mg +Methylcobalamin 1500 mcg + Pregabalin 75 mg | 10s pack(tablets) |
Composition: Telmisartan 20 mg /40 mg tablets
Dosage : Once Daily
Usage : Telverge 20 MG/ 40 MG Tablet is used to treat high blood pressure, prevent stroke and other heart diseases. A proper diet and regular exercise should be maintained along with taking this medicine. This medicine is also highly effective in elderly population who are at higher risk of developing heart diseases.
Approved Indications : In newely diagnosed hypertension
| Brand Names | Composition | Presentation |
|---|---|---|
| Telverge 20/40 | Telmisartan 20 mg /40 mg | 10s pack(tablets) |
Composition: Telmisartan 40 mg tablets + Amlodipine 5 mg tablets
Dosage : Once Daily
Usage : This combination medicine is used for the treatment of high blood pressure and other cardio vascular diseases . Patients are advised to maintain a strict exercise and diet regimen along with this medicine to get the best possible effect
Approved Indications : In diabetic hypertensive patients
| Brand Names | Composition | Presentation |
|---|---|---|
| Telverge AM | Telmisartan 40 mg tablets + Amlodipine 5 mg | 10s pack(tablets) |
Composition: Telmisartan 40 mg tablets + Hydrochlorothiazide 12.5 mg tablets
Dosage : Once Daily
Usage : Telverge H (12.5/40 mg) Tablet is a combination medicine used for the treatment of high blood pressure as a second line therapy.
Approved Indications : In hypertensive patients uncontrolled on monotherapy
| Brand Names | Composition | Presentation |
|---|---|---|
| Telverge H | Telmisartan 40 mg tablets + Hydrochlorothiazide 12.5 mg | 10s pack(tablets) |
Composition: Telmisartan 40 mg tablets + Chlorthalidone 12.5 mg tablets
Dosage : Once Daily
Usage : This combination medicine is used for the treatment of high blood pressure. This medicine may be used when blood pressure could not be controlled by a single medicine or when multiple medicines are needed to achieve desirable blood pressure level.This medicine is not recommended for use in patients below 18 years of age.
Approved Indications : In uncontrolled hypertensive patients
| Brand Names | Composition | Presentation |
|---|---|---|
| Telverge CH | Telmisartan 40 mg tablets + Chlorthalidone 12.5 mg | 10s pack(tablets) |
Composition: Metoprolol succinate extended release tablets 25/ 50 mg
Dosage : Once Daily
Usage : This medication is used to reduce high blood pressure and relieve chest pain caused due to reduced blood flow to the heart. It is also used for treating other complications associated with the heart and blood vessels.
Approved Indications : In management of hypertension with congestive heart failure
| Brand Names | Composition | Presentation |
|---|---|---|
| Ambimet XL 25/50 mg | Metoprolol succinate extended release tablets 25/ 50 mg | 10s pack(tablets) |
Composition: Rosuvastatin 10 mg/ 20 mg tablets
Dosage : Once Daily
Usage : This medication is used to reduce the level of bad cholesterol in the body. It is also used in the treatment of long-term complications such as heart disease or stroke. A proper diet and regular exercise should be maintained along with taking this medicine.
Approved Indications : In patients with Dyslipidemia, Hyperlipidemia, Hypertriglyceridemia, mixed dyslipidemia
| Brand Names | Composition | Presentation |
|---|---|---|
| Stematin 10/20 mg | Telmisartan 40 mg tablets + Chlorthalidone 12.5 mg | 10s pack(tablets) |
Composition: Atorvastatin 10mg , 20 mg, 40 mg tablets
Dosage : Once Daily
Usage : This medication is used to reduce the levels of bad cholesterol and triglycerides in the blood. Along with taking this medicine, a change in diet and regular exercise is recommended. The medicine helps in reducing the long-term cardiovascular risks such as stroke, heart attacks, chest pain etc
Approved Indications : In hypercholesterolemia, Dyslipidemia and prevention of cardiovascular disease
| Brand Names | Composition | Presentation |
|---|---|---|
| Convistat 10/20/40 mg | Atorvastatin 10mg , 20 mg, 40 mg | 10s pack(tablets) |
PRODUCTS : ANTI - INFECTIVES
Staflowin
Generic Name: Flucloxacillin
Strengths Available : 500mg, 1g, 2g
Class : Penicillins
Usage : Staflowin is effective for the treatment of infections due to penicillinase producing staphylococci and other gram positive organisms susceptible to this anti-infective.
Approved Indications : Osteomyelitis and endocarditis. Flucloxacillin is also indicated for use as a prophylactic agent during major surgical procedures when appropriate; for example cardiothoracic and orthopaedic surgery.
MoA : Flucloxacillin is bactericidal with a similar mode of action to benzylpenicillin. It is resistant to staphylococcal penicillinase and therefore active against penicillinase-producing and non-penicillinase-producing staphylococci. It has minimum inhibitory concentrations in the range of 0.25 to 0.5g per ml.
Method of Administration : Intravenous: Dissolve 250 to 500mg in 5 to 10ml of water for injections or 1g in 15 to 20ml of water for injections. Administer by slow intravenous injection (over three to four minutes). Flucloxacillin may also be added to infusion fluids or injected (suitably diluted) into the drip tube over three to four minutes. Flucloxacillin may be added to most intravenous fluids (e.g. water for injections, sodium chloride 0.9%, glucose 5%, sodium chloride 0.18% with glucose 4%).
| Brand Names | Composition | Presentation |
|---|---|---|
| Staflowin | Flucloxacillin 500mg | 6 Capsules strip |
| Staflowin 500mg | Flucloxacillin 500mg Inj. | 1 Vial- lyophilized powder |
| Staflowin 1g | Flucloxacillin 1g Inj. | 1 Vial- lyophilized powder |
| Staflowin 2g | Flucloxacillin 2g Inj. | 1 Vial- lyophilized powder |
Ticogrip
Generic Name: Teicoplanin
Strengths Available : 200mg , 400 mg
Class : Glycopeptides
Usage : Ticogrip is effective in threating Complicated skin and soft tissue , Bone and joint , Hospital acquired pneumonia,Community acquired pneumonia, Complicated urinary tract infections, Infective endocarditis, Peritonitis associated with continuous ambulatory peritoneal dialysis (CAPD), Bacteraemia that occurs in association with any of the indications listed above
Approved Indications : Complicated skin and soft tissue infections, Bone and joint infections, Hospital acquired pneumonia, Community acquired pneumonia, Complicated urinary tract infections, Infective endocarditis, Peritonitis associated with continuous ambulatory peritoneal dialysis (CAPD), Bacteraemia that occurs in association with any of the indications listed above
MoA : Teicoplanin inhibits the growth of susceptible organisms by interfering with cell-wall biosynthesis at a site different from that affected by beta-lactams. Peptidoglycan synthesis is blocked by specific binding to D-alanyl-D-alanine residues.
Method of Administration : Teicoplanin should be administered by the intravenous or intramuscular route. The intravenous injection may be administered either as a bolus over 3 to 5 minutes or as a 30-minute infusion.
Only the infusion method should be used in neonates.
| Brand Names | Composition | Presentation |
|---|---|---|
| Ticogrip 200 | Teicoplanin 200mg Inj. | 1 Vial- lyophilized powder |
| Ticogrip 400 | Teicoplanin 400mg Inj. | 1 Vial- lyophilized powder |
Ciractam
Generic Name: Cefpirome & Sulbactam
Strengths Available : 1.5 g & 3g
Class : Cephalosporins & beta lactamase inhibitors
Usage : Ciractam is effective in treating Lower respiratory tract infections, Complicated Lower and Upper UTI,Bacteremia/Septicaemia, Infections in neutropenic and Immuno-compromised patients, Skin & soft tissues infections, and severe infections in ICU
Approved Indications : Lower respiratory tract infections, Complicated Lower and Upper UTI,Bacteremia/Septicaemia, Infections in neutropenic and Immuno-compromised patients, Skin & soft tissues infections, Severe infections in ICU
MoA : Cefpirome binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.
Sulbactam is a Beta lactamase inhibitor and acts primarily by irreversible inactivation of Beta lactamases.
Method of Administration : 1.5 g -3 gm every 12 hour via IV injection over 3-5 minutes or infuse over 20-30 minutes
| Brand Names | Composition | Presentation |
|---|---|---|
| Ciractam 1.5g | Cefpirome 1g & Sulbactam 500mg Inj. | 1 Vial- lyophilized powder |
| Ciractam 3g | Cefpirome 2g & Sulbactam 1g Inj. | 1 Vial- lyophilized powder |
Sulbitor
Generic Name: Ampicillin & Sulbactam
Strengths Available : 1.5 g & 3g
Class : Penicillin & beta lactamase inhibitors
Usage : Sulbitor is effective in treating community acquired pneumonia , HAP/VAP, Skin and skin structure infections , Intra-abdominal infections, and also used as Surgical prophylaxis
Approved Indications : Community acquired pneumonia , HAP/VAP, Skin and skin structure infections , Intra-abdominal infections, Surgical prophylaxis
MoA : Ampicillin is similar to benzyl penicillin in its bactericidal action against susceptible organisms during the stage of active multiplication. It acts through the inhibition of cell wall mucopeptide biosynthesis. Ampicillin has a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria.
Sulbactam is a lactamase inhibitor and acts primarily by irreversible inactivation of lactamases.
Method of Administration : For IV administration, the dose can be given by slow intravenous injection over at least 10–15 minutes or can also be delivered, in greater dilutions with 50–100 mL of a compatible diluent as an intravenous infusion over 15–30 minutes.
| Brand Names | Composition | Presentation |
|---|---|---|
| Sulbitor 1.5g | Ampicillin1g & Sulbactam 500mg Inj. | 1 Vial- lyophilized powder |
| Sulbitor 3g | Ampicillin 2g & Sulbactam 1g Inj. | 1 Vial- lyophilized powder |
Doxiverge
Generic Name: Doxycycline
Strengths Available : 100mg & 200 mg
Class : Tetracyclines
Usage : Doxiverge is effective in treating Atypical pneumonia, Urinary tract infections, Malaria, Mediterranean spotted fever, Typhus fever, Acute brucellosis, and Cervical chlamydia infections
Approved Indications : Atypical pneumonia, Urinary tract infections, Malaria, Mediterranean spotted fever, Typhus fever, Acute brucellosis, Cervical chlamydia infections
MoA : Doxycycline has bacteriostatic effect blocks protein synthesis at the bacterial ribosome level. The antibiotic connects permanently to 30S (the small ribosome subunit). Resulting in a blocking of the binding of aminoacyl-tRNA (acceptor site) on the mRNA-ribosome complex. This connection terminates the growth of bacterial cells.
Method of Administration : The contents of the vial should be reconstituted with 10 mL of Sterile Water for Injection/nacl/vitamin c
Each 100 mg of doxycycline (i.e., withdraw entire solution from the 100 mg vial) is further diluted with 100 to 1000 mL of the intravenous solutions listed below
0.9% Sodium Chloride Injection
5% Dextrose Injection
Ringer's Injection
| Brand Names | Composition | Presentation |
|---|---|---|
| Doxiverge 100mg | Doxycycline 100mg Inj. | 1 Vial- lyophilized powder |
| Doxiverge PLUS100mg | Doxycycline 100mg Inj. | 1 Vial- lyophilized powder + Ready to administer kit |
| Doxiverge 200g | Doxycycline 200mg Inj. | 1 Vial- lyophilized powder |
Ivtrim
Generic Name: Trimethoprim & Sulphamethoxazole
Strengths Available : 5ml Ampoule
Class : Sulfonamides
Usage : IVTRIM is effective in treating Pneumocystis (Carinii) Jiroveci Pneumonia, Shigella Enteritis, Severe UTIs, toxoplasmosis & Nocardiosis
Approved Indications : Pneumocystis (Carinii) Jiroveci Pneumonia, Shigella Enteritis, Severe UTIs, toxoplasmosis, Nocardiosis
MoA : Co-trimoxazole is generally bactericidal; it acts by sequential blockade of folic acid enzymes in the synthesis pathway. The sulfamethoxazole component inhibits formation of dihydrofolic acid from para-aminobenzoic (PABA), whereas trimethoprim inhibits dihydrofolate reductase.
Method of Administration : It is recommended that Co-Trimoxazole 16 mg/80 mg per ml for Infusion is diluted according to the following schedules:
One ampoule (5 ml) added to 125 ml infusion solution.
Two ampoules (10 ml) added to 250 ml infusion solution.
Three ampoules (15 ml) added to 500 ml infusion solution.
| Brand Names | Composition | Presentation |
|---|---|---|
| Ivtrim | Trimethoprim 80mg & Sulphamethoxazole 400mg Inj. | 1 Vial- lyophilized powder |
Cregnex
Generic Name: Polymyxin B
Strengths Available : 500000 IU, 750000 IU
Class : Polymyxins
Usage : CREGNEX is effective in treating serious infections caused by Gram negative bacteria including LRTI, UTI when commonly used systemic antibacterial agents may be contraindicated or may be ineffective because of bacterial resistance, Post surgical infections in hospitalized patients, Neonatal sepsis, Nosocomial infections & Ventilator associated pneumonia (VAP)
Approved Indications : Serious infections caused by Gram negative bacteria including LRTI, UTI when commonly used systemic antibacterial agents may be contraindicated or may be ineffective because of bacterial resistance, Post surgical infections in hospitalized patients, Neonatal sepsis, Nosocomial infections,Ventilator associated pneumonia (VAP)
MoA : Polymyxin B is a surface active agent which penetrates into and disrupts the bacterial cell membrane. Polymyxin B is polycationic that works by damaging the cell membrane.This effect is bactericidal. Polymyxins are selective for gram negative bacteria that have hydrophobic outer membrane.
Method of Administration : For IV use, dilute the contents in 300-500 ml NS or D5W and infuse over 60-90 minnutes
For IM use ,reconstitute vial with 2 mL SWI , NS, or procaine HCl 1% solution and give deep into upper outer quadrant of gluteal muscles.
Intrathecal (IT): reconstitute vial with10 mL NS; DO NOT use procaine HCl for IT
| Brand Names | Composition | Presentation |
|---|---|---|
| Cregnex 500000IU | Polymyxin B 500000IU Inj. | 1 Vial- lyophilized powder |
| Cregnex 1000000IU | Polymyxin B 1000000IU Inj. | 1 Vial- lyophilized powder |
Precitaz
Generic Name: Piperacillin & Tazobactam
Strengths Available : 2.25 g, 4.5 g
Class : Penicillins and ß lactamase inhibitors
Usage : Prectaz is effective in treating Appendicitis, Peritonitis, Skin and soft tissue infections, Lower respiratory tract infections, infection in neutropenic patients, burn & Intra-abdominal infections
Approved Indications : Appendicitis, Peritonitis, Skin and soft tissue infections, Lower respiratory tract infections, infection in neutropenic patients, burns, Intra-abdominal infections
MoA : Piperacillin inhibits bacterial cell wall synthesis by binding to one or more of the penicillin binding proteins (PBPs); which in turn inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls, thus inhibiting cell wall biosynthesis. Tazobactam inhibits the action of bacterial beta-lactamases. It is added to the extended spectrum beta-lactam antibiotic piperacillin. It broadens the spectrum of piperacillin by making it effective against organisms that express beta-lactamase and would normally degrade piperacillin.
Method of Administration : Intravenous Administration. Reconstituted vial is stable for 24 hours if stored at room temperature or after 48 hours if stored at 2-8 degrees C
| Brand Names | Composition | Presentation |
|---|---|---|
| Precitaz 2.25g | Piperacillin 2g & Tazobactam 0.25g Inj. | 1 Vial- lyophilized powder |
| Precitaz 4.5g | Piperacillin 4g & Tazobactam 0.5g Inj. | 1 Vial- lyophilized powder |
Ivistin/DS/TS/Forte
Generic Name: Colistimethate sodium
Class : Polymyxins
Usage : INVISTIN is effective in treating Serious infections caused by Gram negative bacteria including LRTI, UTI when commonly used systemic antibacterial agents may be contraindicated or may be ineffective because of bacterial resistance, Post surgical infections in hospitalized patients, Neonatal sepsis, Nosocomial infections, & Ventilator –associated pneumonia (VAP)
Approved Indications : serious infections caused by Gram negative bacteria including LRTI, UTI when commonly used systemic antibacterial agents may be contraindicated or may be ineffective because of bacterial resistance, Post surgical infections in hospitalized patients, Neonatal sepsis, Nosocomial infections, Ventilator –associated pneumonia (VAP)
MoA : Colistimethate sodium is a surface active agent which penetrates into and disrupts the bacterial cell membrane. Colistimethate is polycationic that works by damaging the cell membrane.This effect is bactericidal. Polymyxins are selective for gram negative bacteria that have hydrophobic outer membrane.
Method of Administration : Can be given as 50 ml IV infusion over 30 minutes
| Brand Names | Composition | Presentation |
|---|---|---|
| Ivistin | Colistimethate sodium 1M IU Inj. | 1 Vial- lyophilized powder |
| Ivistin DS | Colistimethate sodium 2M IU Inj. | 1 Vial- lyophilized powder |
| Ivistin TS | Colistimethate sodium 3M IU Inj. | 1 Vial- lyophilized powder |
| Ivistin Forte | Colistimethate sodium 4M IU Inj. | 1 Vial- lyophilized powder |
Envade
Generic Name: Imipenem & Cilastatin
Class : Carbapenems
Usage : Envade is effective in treating lower respiratory tract infections, Urinary tract infections , Intra-abdominal infections, Gynecological infections, Life-threatening infections (Septicemia, Endocarditis, Shock), Bone and joint infections, Polymicrobial infections
Approved Indications : Lower respiratory tract infections, Urinary tract infections , Intra-abdominal infections, Gynecological infections, Life-threatening infections (Septicemia, Endocarditis, Shock), Bone and joint infections, Polymicrobial infections
MoA : Envade consists of two components: (1) Imipenem, a derivative of thienamycin, a carbapenem antibiotic; and (2) Cilastatin sodium, a specific inhibitor of dehydropeptidase-I, a renal enzyme which metabolizes and inactivates imipenem. Cilastatin blocks the metabolism of Imipenem in the kidney, so that concomitant administration of Imipenem and Cilastatin allows antibacterial levels of Imipenem to be attained in the urine.
Method of Administration : Each 500 mg dose should be given by intravenous administration over 20 to 30 minutes.
| Brand Names | Composition | Presentation |
|---|---|---|
| Envade | Imipenem 500mg & Cilastatin 500mg Inj. | 1 Vial- lyophilized powder |
Redactis
Generic Name: Tigecycline
Class : Glycylcycline
Usage : REDACTIS is effective in treating Complicated intra-abdominal Infections, Complicated skin & skin structure infections & Community-acquired Pneumonia.
Approved Indications : Complicated intra-abdominal Infections, Complicated skin & skin structure infections , Community-acquired Pneumonia.
MoA : Tigecycline is bacteriostatic and is a protein synthesis inhibitor by binding to the 30S ribosomal sub unit of bacteria and thereby blocking entry of Aminoacyl-tRNA into the A site of the ribosome during prokaryotic translation.
Method of Administration : Intravenous infusion should be administered over approximately 30 to 60 minutes every 12 hours.
| Brand Names | Composition | Presentation |
|---|---|---|
| Redactis | Togecycline 50mg Inj. | 1 Vial- lyophilized powder |
Convictus /Convictus Forte/ Convictus Mega
Generic Name: Cefoperazone & Sulbactam
Class : Cephalosporins and Beta Lactamase Inhibitors
Usage : Effective in treating Respiratory tract infections (Upper and Lower), Urinary tract infections (Upper and Lower) ,Peritonitis, Cholecystitis, Cholangitis, and Other Intra-abdominal infections. Septicemia, Meningitis , Skin and soft tissue Infections, Bone and joint Infections, Pelvic inflammatory disease, Endometritis, Gonorrhea, and other Infections of the genital tract.
Approved Indications : Respiratory tract infections (Upper and Lower) , Urinary tract infections (Upper and Lower) ,Peritonitis, Cholecystitis, Cholangitis, and Other Intra-abdominal infections. Septicemia, Meningitis , Skin and soft tissue Infections
Bone and joint Infections, Pelvic inflammatory disease, Endometritis, Gonorrhea, and other Infections of the genital tract.
MoA : Cefoperazone, a bactericidal antibiotic, inhibits bacterial cell wall synthesis of actively dividing cells by binding to one or more penicillin binding proteins (PBPs). Sulbactam is a Beta-lactamase inhibitor and acts primarily by irreversible inactivation of Beta -lactamases.
Method of Administration : Each vial of sulbactam/cefoperazone should be reconstituted with the appropriate amount of 5% Dextrose in Water, 0.9% Sodium Chloride Injection or Sterile Water for Injection and then diluted to 20 ml with the same solution followed by administration over 15 to 60 minutes.
| Brand Names | Composition | Presentation |
|---|---|---|
| Convictus | Cefoperazone 500mg & Sulbactam 500mg Inj. | 1 Vial- lyophilized powder |
| Convictus Forte | Cefoperazone 1g & Sulbactam 500mg Inj. | 1 Vial- lyophilized powder |
| Convictus Mega | Cefoperazone 2g & Sulbactam 1g Inj. | 1 Vial- lyophilized powder |
Ticlawin
Generic Name: Ticarcillin & Clavulanic acid
Strengths Available : 3.1g
Class : Carboxypenicillin & Beta Lactamase Inhibitor
Usage : Ticlawin is effective in treating Septicemia, Lower respiratory infections, Bone and joint infections, Skin and skin structure infections, Urinary tract infections,and Intra-abdominal infections
Approved Indications : Septicemia, Lower respiratory infections, Bone and joint infections, Skin and skin structure infections, Urinary tract infections, Intra-abdominal infections
MoA : Ticarcillin disrupts bacterial cell wall development by inhibiting peptidoglycan synthesis and/or by interacting with penicillin-binding proteins.
Clavulanic acid is produced by the fermentation of Streptomyces clavuligerus. It is a Beta-lactam structurally related to the penicillins and possesses the ability to inactivate a wide variety of Beta-lactamases by blocking the active sites of these enzymes. Clavulanic acid is particularly active against the clinically important plasmid-mediated Beta-lactamases frequently responsible for transferred drug resistance to penicillins and cephalosporins.
Method of Administration : The 3.1-gram vial should be reconstituted by adding approximately 13 mL of Sterile Water for Injection or Sodium Chloride Injection.Â
Intravenous Infusion: The dissolved drug should be further diluted to desired volume using the recommended solution to a concentration between 10 mg/mL to 100 mg/mL. The solution of reconstituted drug may then be administered over a period of 30 minutes.
| Brand Names | Composition | Presentation |
|---|---|---|
| Ticlawin | Ticarcillin 3g & Clavulanic acid 100mg Inj. | 1 Vial- lyophilized powder |
Zobapime 2.25
Generic Name: Cefepime & Tazobactam
Strengths Available : 2.25g
Class : Cephalosporins
Usage : Zobapime is effective in treating UTI, Febrile neutropenia(FN), Moderate to severe pneumonia, cIAIs, and Uncomplicated SSSI
Approved Indications : UTI, Febrile neutropenia(FN), Moderate to severe pneumonia, cIAIs, Uncomplicated SSSI
MoA : Cefepime -Inhibits bacterial cell wall synthesis by binding to one or more of the penicillin-binding proteins (PBPs) which in turn inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls, thus inhibiting cell wall biosynthesis.
Tazobactam -Tazobactam despite sharing the - lactam - ring that is characteristic of beta-lactam antibiotics. This similarity in chemical structure helps the Tazobactam to act as a inhibitor of beta-lactamase enzyme secreted by certain bacteria that are resistant to beta-lactam antibiotics.
Method of Administration : Cefepime+ Tazobactam can be injected as slow IV over 5 Minutes or as an infusion over 30 Minutes.
| Brand Names | Composition | Presentation |
|---|---|---|
| Zobapime 2.25 | Cefepime 2g & Tazobactam 250mg Inj. | 1 Vial- lyophilized powder |
Zidact 2.25
Generic Name: Ceftazadime & Tazobactam
Strengths Available : 2.25g
Class : Cephalosporins
Usage : Zidact is effective in treating Lower Respiratory Tract Infections- including pneumonia, Skin and Skin-Structure Infections, Urinary Tract Infections, both complicated and uncomplicated, Bacterial Septicemia, Bone and Joint Infections, Gynecologic Infections, Intra-abdominal Infections & Central Nervous System Infections
Approved Indications : Lower Respiratory Tract Infections- including pneumonia, Skin and Skin-Structure Infections, Urinary Tract Infections, both complicated and uncomplicated, Bacterial Septicemia, Bone and Joint Infections, Gynecologic Infections, Intra-abdominal Infections, Central Nervous System Infections
MoA : Ceftazidime- Semisynthetic, broad-spectrum antibacterial derived from cephaloridine and used especially for Pseudomonas and other gram-negative infections in debilitated patients.The bactericidal activity of ceftazidime results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins
Tazobactam -Tazobactam despite sharing the - lactam - ring that is characteristic of beta-lactam antibiotics. This similarity in chemical structure helps the Tazobactam to act as a inhibitor of beta-lactamase enzyme secreted by certain bacteria that are resistant to beta-lactam antibiotics.
Method of Administration : Reconstitute vial with sterile WFI , and further dilute with50ml or 100 ml 0.9 %NaCl, Dextrose 5% , M/6 Sodium Lactate injection & infuse over 30 minutes
| Brand Names | Composition | Presentation |
|---|---|---|
| Zidact 2.25 | Ceftazidime 2g & Tazobactam 250mg Inj. | 1 Vial- lyophilized powder |
Vergiflu
Generic Name: Favipiravir
Strengths Available : 200mg,400mg
Class : Nucleoside, Antiviral
Usage : Mild to Moderate COVID19 Patients,Treatement of Influenza A & B Virus, Ebola virus
Approved Indications : Mild ro Moderate COVID-19 Patients
MoA : The active form, favipiravir-RTP binds to and inhibits the RNA-dependent RNA polymerase (RdRp), preventing viral transcription and replication.Incorporation of favipiravir-RTP into a newly formed RNA strand preventing its elongation and proliferation of the viral genome.
Competitive binding of RNA-dependent RNA polymerase by the favipiravir-RTP and purine nucleosides, which ultimately affects viral replication and transcription.
Method of Administration : Oral Administration, On day 1, 1800mg BID i.e. Morning & Evening 9 tablets respectively. Day2 to Day14 800mg BID i.e.4 tablets Morning & Evening respectively.
PRODUCTS : SUPPORTIVE THERAPY
Oxihalt
Oxihalt
Generic Name: Injection Glutathione
Strengths Available : 600 mg
Class : Tripetides with 3 amino acids glutamic acid, cysteine, and glycine
Approved Indications : Critically ill patients, Liver disorders,Cancer patients,Chronic illness, GI compromised patients,Neurodegenerative disorders
MoA : GSH is an extremely important cell protectant. It directly quenches reactive hydroxyl free radicals, other oxygen-centered free radicals, and radical centers on DNA and other biomolecules. GSH is a primary protectant of skin, lens, cornea, and retina against radiation damage and other biochemical foundations of P450 detoxification in the liver, kidneys, lungs, intestinal, epithelia and other organs
GSH is the essential cofactor for many enzymes that require thiol-reducing equivalents, and helps keep redox-sensitive active sites on enzyme in the necessary reduced state. Higher-order thiol cell systems, the metallothioneins, thioredoxins and other redox regulator proteins are ultimately regulated by GSH levels—and the GSH/GSSG redox ratio. GSH/GSSG balance is crucial to homeostasis—stabilizing the cellular biomolecular spectrum, and facilitating cellular performance and survival.
Method of Administration : IV Drip :Dissolve with 5ml sterile water for injection ; the solution is further diluted into 250 ml or 500ml with Normal saline or 5 % dextrose for IV infusion
IM Injection : :Dissolve with 5ml sterile water for injection . Inject the solution intramascularly, preferably in gluteal region.
| Brand Names | Composition | Presentation |
|---|---|---|
| Oxihalt | Glutathione Injection 600 mg IV/IM | Injectable |
Glutaverge
Molecule: Available as L-alanyl-L-glutamine dipeptide in 20%
Class : Amino acids
Approved Indications : Is indicated as part of an intravenous parenteral nutrition regimen as a supplement to amino acid solutions or an amino acid containing infusion regimen, e.g. in patients in hypercatabolic and/or hypermetabolic states
MoA : Works by helping in gut functioning, the immune system and other essential processes in the body; contributing towards protein construction; strengthening the immune system; helping in metabolism of sugars; reducing the level of cholesterolÂ
Method of Administration : 1.5-2.0 ml /kg /day Can be administered along with TPN or alone Should be mixed with NS in 1 : 1 ratio Infusion rate : 0.5 ml /minute
| Brand Names | Composition | Presentation |
|---|---|---|
| Glutaverge | 50ml | Injectable |
Glutaverge Sachet
Molecule: L Glutamine, Sodium selenite & Zinc sulphate
Class : Nutritional Supplement
Approved Indications : Patients with GI surgery, Critical Illness, Pre and Post operative conditions, Compromised immunity, Burns
Method of Administration : Dissolve the content in 100 ml of water
| Brand Names | Composition | Presentation |
|---|---|---|
| Glutaverge Sachet | Available as Sachet | Injectable |
Prabinex
Molecule: Thiamine Hydrochloride, Riboflavin, Pyridoxine Hydrochloride, Ascorbic Acid, Nicotinamide, Glucose (as Monohydrate) 1000 mg
Class : Water soluble vitamins
Approved Indications : particularly in alcoholism, where a severe depletion of thiamine can lead to Wernicke's encephalopathy, after acute infections, post-operatively, Post Hemodialysis, Sepsis and septic shock
MoA : The B group of vitamins are involved in the development and maintenance of the nervous system (brain and nerves) and the formation of blood cells. Vitamin C is an antioxidant and is responsible for maintaining healthy cell structure and producing an important protein, known as collagen, which is found in the skin, bone, cartilage and tendons.
Method of Administration : Prabinex Intravenous High Potency, Concentrate for Solution for Infusion should be administered by drip infusion. Equal volumes of the contents of ampoules number 1 and 2 should be added to 50 ml to 100 ml physiological saline or 5% glucose and infused over 30 minutes
| Brand Names | Composition | Presentation |
|---|---|---|
| Prabinex | Two ampoules of 5 ml | Injectable |
Prabinex HD
Molecule: Ascorbic acid
Class : Water soluble vitamins
Approved Indications : Sepsis related organ failure, Adjuvant therapy in viral infections, Synergism with antibiotics for infections caused by Streptococcal, Staphylococcal , E.coli, and Pseudomonas strains. Supportive therapy in ARDS, and Acute Lung Injury, Supportive therapy in patients with Cancer by inhibiting tumor growth and synergizing with Chemotherapy agents
MoA : Ascorbic acid is an essential water soluble vitamin that acts as a cofactor and antioxidant. Ascorbic acid is an electron donor used for collagen hydroxylation, carnitine biosynthesis, and hormone/amino acid biosynthesis. It is required for connective tissue synthesis as well as iron absorption and storage
Method of Administration : 1.5 g of Prabinex HD is diluted with 50 ml of 0.9 % saline
| Brand Names | Composition | Presentation |
|---|---|---|
| Prabinex HD | 1.5 g | Injectable |
Vosimol/Vosimol Plus
Molecule: Inj. Paracetamol IV
Class : Analgesic and antipyretic
Approved Indications : Indicated for the short-term treatment of moderate pain, especially following surgery
For the short-term treatment of fever, when administration by intravenous route is clinically justified
In urgent need to treat pain or hyperthermia and / or when other routes of administration are not possible
MoA : The exact mechanism of action of paracetamol is still unclear
It is thought to exert its analgesic activity by inhibiting the synthesis of prostaglandins in the CNS (central acting) and peripherally blocking pain impulse generation
It is thought to exert its analgesic activity by inhibiting the synthesis of prostaglandins in the CNS (central acting) and peripherally blocking pain impulse generation
Method of Administration : The paracetamol solution is administered as a 15-minute intravenous infusion.
| Brand Names | Composition | Presentation |
|---|---|---|
| Vosimol/Vosimol Plus | 1000 mg / 100 ml | Injectable |
Panverge D
Composition: Pantoprazole 40 + Domperidone 30 mg
Dosage : Once Daily or Twice Dialy as advised by physician
Usage : Its a proton pump inhibitor used in the treatment of stomach ulcers, gastroesophageal reflux disease (GERD) and other acidity-related disorders. It decreases the acid produced in the stomach and helps in promoting healing of ulcers
Approved Indications : In GERD and other acidity related disorders
| Brand Names | Composition | Presentation |
|---|---|---|
| Panverge D | Pantoprazole 40 + Domperidone 30 mg | 10s pack(tablets) |
Prabinex HD
Molecule: Ascorbic acid
Class : Water soluble vitamins
Approved Indications : Sepsis related organ failure, Adjuvant therapy in viral infections, Synergism with antibiotics for infections caused by Streptococcal, Staphylococcal , E.coli, and Pseudomonas strains. Supportive therapy in ARDS, and Acute Lung Injury, Supportive therapy in patients with Cancer by inhibiting tumor growth and synergizing with Chemotherapy agents
MoA : Ascorbic acid is an essential water soluble vitamin that acts as a cofactor and antioxidant. Ascorbic acid is an electron donor used for collagen hydroxylation, carnitine biosynthesis, and hormone/amino acid biosynthesis. It is required for connective tissue synthesis as well as iron absorption and storage
Method of Administration : 1.5 g of Prabinex HD is diluted with 50 ml of 0.9 % saline
| Brand Names | Composition | Presentation |
|---|---|---|
| Prabinex HD | 1.5 g | Injectable |
Tolerab D
Composition: Rabeprazole 20 mg + Domperidone 30 mg
Dosage : Once Daily
Usage : This tablet is used in the treatment of stomach ulcers, Gastroesophageal reflux disease (GERD) and other acidity related disorders by decreasing the acid produced in the stomach.
Approved Indications : In GERD and other acidity related disorders
| Brand Names | Composition | Presentation |
|---|---|---|
| Tolerab D | Rabeprazole 20 mg + Domperidone 30 mg | 10s pack(tablets) |
Tancyvit
Composition: Multi vitamin , Minerals & Antioxidant soft gel capsules
Dosage : Once or Twice Daily as recommended
Usage : Capsule is a combination of essential minerals and vitamins that helps in blood formation, bone strengthening, and other vital functions. It is used to treat vitamin deficiencies, anemia, and nerve-related symptoms. This capsule helps to increase physical strength, immunity power. It improves nerve function and blood circulation. It enhances the energy levels and supports in weight management.
Approved Indications : To restore nutritional deficiency states
| Brand Names | Composition | Presentation |
|---|---|---|
| Tancyvit | Multi vitamin , Minerals & Antioxidant soft gel capsules | 10s pack(Capsules) |
Divify
Composition: VITAMIN D3 60000 IU ORALLY DISINTEGRATING STRIPS
Dosage : One Strip/Week
Usage : In vitamin D deficiency states and prevent complications of Hypovitaminosis, Post menopausal osteoporosis, As an adjunct in Diabetes
Approved Indications : Hypovitaminosis, Post menopausal osteoporosis, As an adjunct in Diabetes
| Brand Names | Composition | Presentation |
|---|---|---|
| Divify | VITAMIN D3 60000 IU ORALLY DISINTEGRATING | 8 Strips |
Prabinex 500 mg
Composition: ascorbic acid 500 mg
Approved Indications : Benefits are as follows:
* Contribute to normal functioning of immune system
* Boosts immune system to effectively protect from Covid 19
* Powerful antioxidant, relieves symptoms of asthma
* Protects against cough and common cold
* Prevents cancer and heart disease - aids lowering hypertensio
| Brand Names | Composition | Presentation |
|---|---|---|
| Prabinex 500 mg | Ascorbic acid 500 mg | 15s packing(tablets) |
Prabinex Z
Composition: Ascorbic acid 500 mg + zinc 20 mg
Approved Indications : Benefits are as follows:
* Reduced inflamaton
* Protectsfrom free radicals and oxidaive stress
* Enhances immunity system
| Brand Names | Composition | Presentation |
|---|---|---|
| Prabinex Z | Ascorbic acid 500 mg + zinc 20 mg | 15s packing(tablets) |
PRODUCTS : ANTI DIABETIC
Tenlicreat
Composition: TENELIGLIPTIN 20 mg tablet
Dosage : Once Daily
Usage : Teneligliptin is a Novel Dipeptidyl Peptidase IV inhibitors for the treatment of type 2 diabetes with minimal risk of hypoglycemia and weight gain. TENeLIgliptin act on inCRETins with elevation of activated glucagon-like peptide 1 (GLP-1) levels and the resulting suppression of postprandial hyperglycemia.
Approved Indications : In treatment of Type 2 diabetes mellitus
| Brand Names | Composition | Presentation |
|---|---|---|
| Tenlicret | Teneligliptin 20 mg | 10s pack(tablets) |
Tenlicret M Plus
Composition: TENELIGLIPTIN 20 + METFORMIN 1000 mg tablet
Dosage : Once Daily
Usage : Teneligliptin is a Novel Dipeptidyl Peptidase IV inhibitors for the treatment of type 2 diabetes with minimal risk of hypoglycemia and weight gain. TENeLIgliptin act on inCRETins with elevation of activated glucagon-like peptide 1 (GLP-1) levels and the resulting suppression of postprandial hyperglycemia.
Approved Indications : In treatment of Type 2 diabetes mellitus
| Brand Names | Composition | Presentation |
|---|---|---|
| Tenlicret M Plus | TENELIGLIPTIN 20 + METFORMIN 1000 mg tablet | 10s pack(tablets) |
Zyvana
Composition: Glimepiride 1mg/2mg tablets
Dosage : Once Daily
Usage : Glimipiride 1/2 mg tablet is a long-acting oral anti-diabetic which lower the blood sugar level. It is used only in patients diagnosed with Type II Diabetes. It may be used along with Insulin or other medicines in order to achieve better control over the blood sugar levels. This medicine, when taken along with a controlled diet and regular exercise routine, may give better results.
Approved Indications : For Type 2 diabetes mellitus patients for glycemic control
| Brand Names | Composition | Presentation |
|---|---|---|
| Zyvana | Glimepiride 1mg/2mg | 10s pack(tablets) |
Tenlicret
Composition: TENELIGLIPTIN 20 mg tablet
Dosage : Once Daily
Usage : Teneligliptin is a Novel Dipeptidyl Peptidase IV inhibitors for the treatment of type 2 diabetes with minimal risk of hypoglycemia and weight gain. TENeLIgliptin act on inCRETins with elevation of activated glucagon-like peptide 1 (GLP-1) levels and the resulting suppression of postprandial hyperglycemia.
Approved Indications : In treatment of Type 2 diabetes mellitus
| Brand Names | Composition | Presentation |
|---|---|---|
| Tenlicret | Teneligliptin 20 mg | 10s pack(tablets) |
Tenlicret M
Composition: TENELIGLIPTIN 20 + METFORMIN 500 mg tablet
Dosage : Once Daily
Usage : Teneligliptin is a Novel Dipeptidyl Peptidase IV inhibitors for the treatment of type 2 diabetes with minimal risk of hypoglycemia and weight gain. TENeLIgliptin act on inCRETins with elevation of activated glucagon-like peptide 1 (GLP-1) levels and the resulting suppression of postprandial hyperglycemia.
Approved Indications : In treatment of Type 2 diabetes mellitus
| Brand Names | Composition | Presentation |
|---|---|---|
| Tenlicret M | TENELIGLIPTIN 20 + METFORMIN 500 mg | 10s pack(tablets) |
Zyvana M1/M2
Composition: Glimepiride 1mg/2mg + Metformin 500 mg tablets
Dosage : Once Daily
Usage : It is an effective choice medicine used to control high blood glucose levels in patients with type II diabetes. Patients are advised to maintain a strict exercise and diet regimen along with this medicine to get the best possible effect.
Approved Indications : For Type 2 diabetes mellitus patients inadequately controlled on monotherapy.
| Brand Names | Composition | Presentation |
|---|---|---|
| Zyvana M1/M2 | Glimepiride 1mg/2mg + Metformin 500 mg | 10s pack(tablets) |
Composition: Glimepiride 1mg/2mg + Metformin 500 mg tablets
Dosage : Once Daily
Usage : It is an effective choice medicine used to control high blood glucose levels in patients with type II diabetes. Patients are advised to maintain a strict exercise and diet regimen along with this medicine to get the best possible effect.
Approved Indications : For Type 2 diabetes mellitus patients inadequately controlled on monotherapy.
| Brand Names | Composition | Presentation |
|---|---|---|
| Zyvana M1/M2 | Glimepiride 1mg/2mg + Metformin 500 mg | 10s pack(tablets) |
Zyvana M2 Forte
Composition: Glimepiride 2mg + Metformin 1000 mg tablets
Dosage : Once Daily
Usage : It is an effective choice medicine used to control high blood glucose levels in patients with type II diabetes. Patients are advised to maintain a strict exercise and diet regimen along with this medicine to get the best possible effect.
Approved Indications : For Type 2 diabetes mellitus patients uncontrolled on low dose dual therapy.
| Brand Names | Composition | Presentation |
|---|---|---|
| Zyvana M2 Forte | Glimepiride 2mg + Metformin 1000 mg | 10s pack(tablets) |
Confirmin 500/1000 mg
Composition: Metformin Hydrochloride 500 & 1000 mg
Dosage : Once Daily or Twice Dialy as advised by physician
Usage : Metformin 500 mg/ 1000 mg Tablet is an effective first choice medicine used to control high blood glucose levels in patients with type II diabetes. Patients are advised to maintain a strict exercise and diet regimen along with this medicine to get the best possible effect. It helps in minimizing the risk of diabetes-associated complications such as blindness, kidney damage, stroke and heart attack.
Approved Indications : As a first line therapy in newely diagnosed diabetic patients
| Brand Names | Composition | Presentation |
|---|---|---|
| Confirmin 500/1000 mg | Metformin Hydrochloride 500 & 1000 mg | 15s packing(tablets) |
Numbnil
Composition: Ashwagandha, Piper Longum, Zingiber Officinale,Mustard Oil & Aleovera-a total foot care cream
Dosage : Apply 3 times a day in palms,soles & other affected areas
Usage : Total foot care cream effective in Burning feet syndrome, Numbness, Tingling pain, shooting pain in Soles or palms.
Approved Indications : Burning feet syndrome, Numbness, Tingling pain, shooting pain in Soles or palms
| Brand Names | Composition | Presentation |
|---|---|---|
| Numbnil | Ashwagandha, Piper Longum, Zingiber Officinale,Mustard Oil & Aleovera | 1 tube(cream) |
Entivon
Composition: Methylcobalamin 750 mcg + Pregabalin 75 mg capsules
Dosage : Once/Twice daily as recommended
Usage : Level “A” recommended for relief of painful diabetic peripheral neuropathy with excellent tolerability.
Approved Indications : In management of mild to moderate stages of Diabetic Peripheral Neuropathy
| Brand Names | Composition | Presentation |
|---|---|---|
| Entivon | Methylcobalamin 750 mcg + Pregabalin 75 mg | 10s pack(capsules) |
Entivon Plus
Composition: Nortriptyline 10 mg +Methylcobalamin 1500 mcg + Pregabalin 75 mg SR tablets
Dosage : Once Daily
Usage : This medication is used to treat pain caused by nerve damage due to diabetes or spinal cord injury. This medication is also used to treat pain in people with fibromyalgia.
Approved Indications : In management of advanced stages of diabetic peripheral neuropathy
| Brand Names | Composition | Presentation |
|---|---|---|
| Entivon Plus | Nortriptyline 10 mg +Methylcobalamin 1500 mcg + Pregabalin 75 mg | 10s pack(tablets) |
PRODUCTS : ANTI HYPERTENSIVES
Telverge 20/40
Composition: Telmisartan 20 mg /40 mg tablets
Dosage : Once Daily
Usage : Telverge 20 MG/ 40 MG Tablet is used to treat high blood pressure, prevent stroke and other heart diseases. A proper diet and regular exercise should be maintained along with taking this medicine. This medicine is also highly effective in elderly population who are at higher risk of developing heart diseases.
Approved Indications : In newely diagnosed hypertension
| Brand Names | Composition | Presentation |
|---|---|---|
| Telverge 20/40 | Telmisartan 20 mg /40 mg | 10s pack(tablets) |
Telverge AM
Composition: Telmisartan 40 mg tablets + Amlodipine 5 mg tablets
Dosage : Once Daily
Usage : This combination medicine is used for the treatment of high blood pressure and other cardio vascular diseases . Patients are advised to maintain a strict exercise and diet regimen along with this medicine to get the best possible effect
Approved Indications : In diabetic hypertensive patients
| Brand Names | Composition | Presentation |
|---|---|---|
| Telverge AM | Telmisartan 40 mg tablets + Amlodipine 5 mg | 10s pack(tablets) |
Telverge H
Composition: Telmisartan 40 mg tablets + Hydrochlorothiazide 12.5 mg tablets
Dosage : Once Daily
Usage : Telverge H (12.5/40 mg) Tablet is a combination medicine used for the treatment of high blood pressure as a second line therapy.
Approved Indications : In hypertensive patients uncontrolled on monotherapy
| Brand Names | Composition | Presentation |
|---|---|---|
| Telverge H | Telmisartan 40 mg tablets + Hydrochlorothiazide 12.5 mg | 10s pack(tablets) |
Telverge CH
Composition: Telmisartan 40 mg tablets + Chlorthalidone 12.5 mg tablets
Dosage : Once Daily
Usage : This combination medicine is used for the treatment of high blood pressure. This medicine may be used when blood pressure could not be controlled by a single medicine or when multiple medicines are needed to achieve desirable blood pressure level.This medicine is not recommended for use in patients below 18 years of age.
Approved Indications : In uncontrolled hypertensive patients
| Brand Names | Composition | Presentation |
|---|---|---|
| Telverge CH | Telmisartan 40 mg tablets + Chlorthalidone 12.5 mg | 10s pack(tablets) |
Ambimet XL 25/50 mg
Composition: Metoprolol succinate extended release tablets 25/ 50 mg
Dosage : Once Daily
Usage : This medication is used to reduce high blood pressure and relieve chest pain caused due to reduced blood flow to the heart. It is also used for treating other complications associated with the heart and blood vessels.
Approved Indications : In management of hypertension with congestive heart failure
| Brand Names | Composition | Presentation |
|---|---|---|
| Ambimet XL 25/50 mg | Metoprolol succinate extended release tablets 25/ 50 mg | 10s pack(tablets) |
PRODUCTS : LIPID LOWERING
Stematin 10/20 mg
Composition: Rosuvastatin 10 mg/ 20 mg tablets
Dosage : Once Daily
Usage : This medication is used to reduce the level of bad cholesterol in the body. It is also used in the treatment of long-term complications such as heart disease or stroke. A proper diet and regular exercise should be maintained along with taking this medicine.
Approved Indications : In patients with Dyslipidemia, Hyperlipidemia, Hypertriglyceridemia, mixed dyslipidemia
| Brand Names | Composition | Presentation |
|---|---|---|
| Stematin 10/20 mg | Telmisartan 40 mg tablets + Chlorthalidone 12.5 mg | 10s pack(tablets) |
Convistat 10/20/40 mg
Composition: Atorvastatin 10mg , 20 mg, 40 mg tablets
Dosage : Once Daily
Usage : This medication is used to reduce the levels of bad cholesterol and triglycerides in the blood. Along with taking this medicine, a change in diet and regular exercise is recommended. The medicine helps in reducing the long-term cardiovascular risks such as stroke, heart attacks, chest pain etc
Approved Indications : In hypercholesterolemia, Dyslipidemia and prevention of cardiovascular disease
| Brand Names | Composition | Presentation |
|---|---|---|
| Convistat 10/20/40 mg | Atorvastatin 10mg , 20 mg, 40 mg | 10s pack(tablets) |
Product Line
With a distinctive presence in the core therapeutic areas viz. critical care and cardiometabolic syndromes our products have proved to be efficient and effective over the short span of time. As experts in the realms of critical care, the company supplies life-saving anti-infective antidotes to various eminent hospitals all across India.
The company has successfully launched a smorgasbord of superior, innovative and affordable products that address the cardiometabolic division and hi-end quality products in the management of DPN: Diabetic Peripheral Neuropathy and for Vitamin D deficiency.
In a bid to further empower their existence in these aforesaid sectors, the company has resolved to introduce innovative, intelligent and improved formulations as quality solutions to these segments. On a sincere note, Converge has aimed to emerge as market-leaders in the divisions of critical care and cardiometabolic, and create a forte in other specialty sectors viz. nephrology, oncology and dermatology.
Indeed, the company’s growth is aided by cost-effective drug development and substantial manufacturing.
